In vitro biophysics project – improving efficacy of pulmonary surfactant to increase survival following mechanical ventilation of lung injury patients.

BACKGROUND:  Our lab discovered that an existing molecule lowers surface tension in the lungs and, during mechanical ventilation of injured lungs, reduces ventilation injury and improves oxygenation.  The molecule is a promising potential therapeutic for treating acute lung injury, such as that caused by COVID-19.

OPENING/PROJECT:  An opening is available for a Ph.D. student to work on a biophysics project.  The project will comprise working with an in vitro surfactometer to replicate the effect of the therapeutic on pulmonary surfactant and investigate mechanism of action.

The project will focus on biophysical investigations and lead to molecular modification studies. 

THE PI:  Dr. Perlman holds a bachelor’s degree in mechanical engineering from MIT and a Ph.D. in biomedical engineering from Northwestern University.  She trained in pulmonary physiology as a postdoctoral fellow at Columbia University.  She is an expert on surface tension effects on lung micromechanics in the context of ventilator induced lung injury.

ENVIRONMENT:  Stevens Institute of Technology is located on a beautiful campus overlooking the Hudson River and directly across from New York City.  The Biomedical Engineering department at Stevens is a supportive environment in which to work.

REQUIREMENTS: The ideal candidate will have a bachelor’s degree in biophysics, biomedical engineering, chemistry, physics or a closely-related discipline.  The candidate will preferably have a master’s degree and U.S. citizenship or permanent residency.  The candidate will be hard-working, inquisitive, creative, logical, disciplined and organized, with strong oral and written communication skills.

TO APPLY:  Please email Dr. Perlman  at cperlman@stevens.edu expressing interest in the position and including copies of your CV; transcripts; and scores for the GRE, if available, and any other standardized tests taken.

DEADLINE: Applications are being accepted for the fall 2025 semester.  Position will remain open through mid-August or until filled.

About Stevens Institute of Technology

Stevens is an equal opportunity employer that is building a diverse faculty, staff and student body and strongly encourages applications from female and minority candidates as well as veterans and individuals with disabilities. Stevens is an NSF ADVANCE institution committed to equitable practices and policies.

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